Case patients were selected among adolescents who were
hospitalized with Covid-19 as the primary reason for admission or who had a clinical syndrome
consistent with acute Covid-19 (one or more symptoms of fever, cough,
shortness of breath, loss of taste, loss of smell, gastrointestinal symptoms,
respiratory support, or new pulmonary findings on chest imaging). All case
patients had positive results for SARS-CoV-2 on reverse
transcriptase–polymerase-chain-reaction (RT-PCR) assay or on antigen testing
those without Covid-19–like symptoms who may or may not have undergone SARS-CoV-2
testing
Patients were considered to have received Covid-19
vaccination based on source documentation or by plausible self-report
Among the case patients, the median age was 16 years, 74% had at least one underlying
condition (including obesity), and 70% attended an in-person school
Among the controls, the median age was 15 years, 70% had at least one underlying
condition, and 70% attended an in-person school.
Underlying
conditions, which included obesity, were common, both among adolescents who
were vaccinated (73%) and those who were unvaccinated (71%). Respiratory and endocrine disorders
were more prevalent among case patients than among
controls ; neurologic
or neuromuscular disorders and immunosuppressive or autoimmune disorders
were more prevalent among controls than among case
patients.
RAISON PRINCIPALE DE L’ADMISSION À L’HÔPITAL :
TABLE S2. Primary admission diagnosis among 37
hospitalized patients* with SARS-CoV-2 positive test who were hospitalized for
a non-COVID-19 reason
Psychiatric admission (41%) / Trauma (24%) / Shunt
malfunction (8%) / Abscess (3%) / Cellulitis (3%) / Cholelithiasis (3%)
/ Feeding tube malfunction (3%) / Gynecologic (3%) / Medication infusion
(3%) / New cancer diagnosis (3%) / Post-operative complication (3%) / Suicidal
ideation (3%) / Trauma (3%)
COMORBIDITÉS :
TABLE S3. Underlying conditions and vaccination
status among COVID-19 case-patients with ECMO or death
1 Respiratory system disorder, asthma, other chronic
condition* / 2 Respiratory system disorder, asthma, endocrine disorder,
Type I
diabetes, other chronic condition* / 3 Respiratory system disorder, asthma, other chronic
condition* / 4 Endocrine disorder, Type II diabetes, other chronic
condition* / 5 Respiratory system disorder and asthma / 6 Respiratory system disorder and other chronic condition* / 7 Disorder of cardiovascular system and other chronic
condition* / 8 Respiratory system disorder and asthma / 9 Disorder of cardiovascular system, endocrine disorder,
other chronic condition* / 10 Other chronic condition* / 11 Other chronic condition* / 12 Respiratory system disorder, asthma, endocrine disorder / 13 Respiratory system disorder, Endocrine disorder, Type II
Diabetes, other chronic condition* / 14 Endocrine disorder, Type I Diabetes / 15 Disorder of cardiovascular system, neurologic or
neuromuscular disorder, non-oncologic immunosuppressive disorder,
endocrine disorder, other chronic condition* / 16 Endocrine disorder, Type II diabetes
*Other chronic
conditions included, but not limited to, obesity,
rheumatologic/autoimmune disorder, hematologic disorder, renal or urologic
dysfunction, gastrointestinal/hepatic disorder, metabolic or confirmed or
suspected genetic disorder, or atopic or allergic condition.