Vulpes vulpes

@bubu12
 

The BMJ has reviewed the documents, which show that regulators had major concerns over unexpectedly low quantities of intact mRNA in batches of the vaccine developed for commercial production.

EMA scientists tasked with ensuring manufacturing quality [...] worried about “truncated and modified mRNA species present in the finished product.” Among the many files leaked to The BMJ, an email dated 23 November by a high ranking EMA official outlined a raft of issues. In short, commercial manufacturing was not producing vaccines to the specifications expected, and regulators were unsure of the implications. EMA responded by filing two “major objections” with Pfizer, along with a host of other questions it wanted addressed.

The email identified “a significant difference in % RNA integrity/truncated species” between the clinical batches and proposed commercial batches—from around 78% to 55%. The root cause was unknown and the impact of this loss of RNA integrity on safety and efficacy of the vaccine was “yet to be defined,” the email said.

@bubu12
 

The Pfizer/BioNTech vaccine (BNT162b2) is composed of an mRNA that produces a membrane-anchored full-length spike protein. The mouse studies suggest that an untruncated form of the S1 protein like this may cause a microvasculopathy in tissues that express much ACE2 receptor. A truncated form of S1 was much less damaging in mice.

 

While there are pieces to this puzzle that have yet to be worked out, it appears that the viral spike protein that is the target of the major SARS-CoV-2 vaccines is also one of the key agents causing the damage to distant organs that may include the brain, heart, lung, and kidney. Before any of these vaccines are approved for widespread use in humans, it is important to assess in vaccinated subjects the effects of vaccination on the heart [...].

 

Vaccinated patients could also be tested for distant tissue damage in deltoid area skin biopsies [...]. As important as it is to quickly arrest the spread of the virus by immunizing the population, it would be vastly worse if hundreds of millions of people were to suffer long-lasting or even permanent damage to their brain or heart microvasculature as a result of failing to appreciate in the short-term an unintended effect of full-length spike protein-based vaccines on these other organs.

@bubu12
 

Royaume Uni

9 décembre 2020 – 21 mars 2021

283 morts suite au vaccin Pfizer !

@Super Cochon
 

Le contenu de ce FAUX-vaccin est terrifiant !

… et ce n’est que la partie visible de l’iceberg  !

Pourquoi au début de la crise AstraZeneca on parlait de lots défectueux  ? Y a-t’il des lots avec des compositions différentes  ? Comme le vaccin est encore expérimental, en phase de test, seraient-ils en train d’essayer plusieurs versions  ?

Est-ce que l’État vérifie que la composition des vaccins correspond bien à ce qui a été précisé dans les contrats  ?

@LUCA
 

« la lumière luit dans les ténèbres, et les ténèbres ne l’ont pas saisie. »
 
Joyeuses Pâques !