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sur Laurent Montesino à coeur ouvert


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Vulpes vulpes Vulpes vulpes 17 août 09:14

@MYTH©bubu

MYTH©bubu  : il y a une quinzaine de RCT et de meta-analyses qui contredisent toutes [les] conneries sur l’hydroxychloroquine

 

Depuis 16 mois, au moins, pr. Raoult applique son protocole (HCQ+AZM+Zn), que même un enfant de 5 ans connaît maintenant, mais vous vous forcez à l’ignorer, en restant bloqué sur l’HCQ.

 

Pourquoi l’HCQ + AZM ?

Azithromycin (AZM) is a commonly used macrolide antibiotic that has antiviral properties mainly attributed to reduced endosomal transfer of virions as well as established anti-inflammatory effects (Pani et al., 2020). French reports indicated that AZM in combination with HCQ was associated with reduced durations of viral shedding, fewer hospitalizations, and reduced mortality as compared to those untreated (Lagier et al., 2020 ; Million et al., 2020). In a large observational inpatient study (n = 2451), those who received AZM alone had an adjusted hazard ratio for mortality of 1.05, 95% CI 0.68-1.62, P = 0.83 (Colunga Biancatelli et al., 2020). The combination of HCQ and AZM has been considered a standard of care outside the US for COVID-19 in more than 300,000 older adults with multiple comorbidities (Risch, 2020). AZM like HCQ can prolong the QTc in < 1% of patients, yet has demonstrated safety in co-administration with HCQ (Huang et al., 2020). A reasonable regimen is 250 mg po bid for 5 to 30 days

Multifaceted highly targeted sequential multidrug treatment of early ambulatory high-risk SARS-CoV-2 infection (COVID-19)

Rev. Cardiovasc. Med. 2020 vol. 21(4), 517–530

 

Si votre quinzaine de RCT et de meta-analyses contredisent toutes [les] conneries sur l’hydroxychloroquine, elles doivent reussir à contredire également les conneries sur l’HCQ+AZM !!!

Comme précisé plus haut, j’attends les 8 autres RCT / Méta-analyses et après on peut les regarder plus en détail  !

Bon courage !

 

Heil Μπουρλά !


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