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Commentaire de Vulpes vulpes

sur 25 mai 2021 - Pr Didier Raoult : COVID, Recherche, Curiosité & Vérités internationales


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Vulpes vulpes Vulpes vulpes 31 mai 2021 15:34

@PFIZE®baba

bubu12 : l’efficacité est démontrée par les études de phases 3 qui sont publiées. Ce n’est pas une nouveauté que les phases 3 soient réalisées par le fabriquant


Corollary 6 : The hotter a scientific field (with more scientific teams involved), the less likely the research findings are to be true. This seemingly paradoxical corollary follows because, as stated above, the PPV of isolated findings decreases when many teams of investigators are involved in the same field. This may explain why we occasionally see major excitement followed rapidly by severe disappointments in fields that draw wide attention. With many teams working on the same field and with massive experimental data being produced, timing is of the essence in beating competition. Thus, each team may prioritize on pursuing and disseminating its most impressive “positive” results. “Negative” results may become attractive for dissemination only if some other team has found a “positive” association on the same question. In that case, it may be attractive to refute a claim made in some prestigious journal. The term Proteus phenomenon has been coined to describe this phenomenon of rapidly alternating extreme research claims and extremely opposite refutations [29]. Empirical evidence suggests that this sequence of extreme opposites is very common in molecular genetics [29].

 


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